Phosphonosuccinic acid → HCID 13955541、化合物

反応式

[P:1]([CH:5]([C:10]([OH:12])=[O:11])[CH2:6][C:7]([OH:9])=[O:8])([OH:4])([OH:3])=[O:2].P([O-])(OCC)O[CH2:15]C>>[P:1]([C:5]([C:10]([OH:12])=[O:11])([CH2:6][C:7]([OH:9])=[O:8])[CH3:15])([OH:4])([OH:3])=[O:2]

参加物

反応物 2

HCID 110710Phosphonosuccinic acid

HCID 3780918Diethylphosphite

生成物 1

HCID 13955541HCID 13955541、化合物

実験手順

1-Phosphono-1,2-ethane-dicarboxylic acid can be prepared by reaction of maleic ester (diethyl maleate) with diethyl phosphite in the presence of sodium alcoholate followed by acid saponification of the ester. 2-Phosphono-2,3-propane dicarboxylic acid can be obtained in the same manner with addition of the step of reacting the mixture with methyl chloride before the saponification step.

出典と根拠

ORDレコード: ord-82b95238a0f64163a0d157bd38cce717
出典データセット: uspto-grants-1978_04
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US04086334

反応ノート

読み込み中…

参加物