Acetic Anhydride → 3-Methoxycarbonyl-2-benzylidenepropanoic acid

HRID 2083711ノート

反応式

HRID 2083711 の反応式
[C:1]([CH2:4][C:5](=[CH:9][C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1)[C:6]([OH:8])=[O:7])([OH:3])=[O:2].[C:16](OC(=O)C)(=O)C>>[CH3:16][O:2][C:1]([CH2:4][C:5](=[CH:9][C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1)[C:6]([OH:8])=[O:7])=[O:3]

参加物

3

反応物 2

HCID 7918Acetic AnhydrideHCID 2229982-(Phenylmethylene)butanedioic acid

生成物 1

HCID 541581613-Methoxycarbonyl-2-benzylidenepropanoic acid

実験手順

2-Carboxymethyl-3-phenylpropenoic acid (4.1 g.) and acetic anhydride (9 ml.) are heated in the steam bath for 70 minutes. The mixture is concentrated to dryness and the residue triturated with ether, yield 3.6 g. This anhydride is dissolved in 7 ml. of methanol and heated in the steam bath for 1 hour.

後処理

  1. concentrationThe mixture is concentrated to dryness
  2. customthe residue triturated with ether, yield 3.6 g
  3. dissolutionThis anhydride is dissolved in 7 ml
  4. temperatureof methanol and heated in the steam bath for 1 hour

出典と根拠

ORDレコード
ord-4f95cac6eeb5427a97011d187ecfc144
出典データセット
uspto-grants-1978_04
特許番号
US04086338

反応ノート

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