1-[4-(4-benzyloxyphenyl)butyl)-1H-1,2,3-triazole → 4-(4-[1,2,3]Triazol-1-yl-butyl)phenol

HRID 2084371ノート

反応式

HRID 2084371 の反応式
C([O:8][C:9]1[CH:14]=[CH:13][C:12]([CH2:15][CH2:16][CH2:17][CH2:18][N:19]2[CH:23]=[CH:22][N:21]=[N:20]2)=[CH:11][CH:10]=1)C1C=CC=CC=1.[H][H]>CO.[C].[Pd]>[N:19]1([CH2:18][CH2:17][CH2:16][CH2:15][C:12]2[CH:11]=[CH:10][C:9]([OH:8])=[CH:14][CH:13]=2)[CH:23]=[CH:22][N:21]=[N:20]1

参加物

5

反応物 2

HCID 227333491-[4-(4-benzyloxyphenyl)butyl)-1H-1,2,3-triazoleHCID 178418361HCID 178418361、化合物

生成物 1

HCID 121094944-(4-[1,2,3]Triazol-1-yl-butyl)phenol収率 99.8%

試薬・触媒・溶媒 2

HCID 178418390HCID 178418390、化合物触媒HCID 887Methanol溶媒

実験手順

1-[4-(4-benzyloxyphenyl)butyl]-1H-1,2,3-triazole (0.38 g) was dissolved in methanol (7.6 ml); 10% palladium carbon (0.1 g) was added, followed by vigorous stirring in a hydrogen atmosphere for 14 hours. The catalyst was filtered off; the filtrate was concentrated to dryness under reduced pressure to yield the titled compound (0.268 g) as a crystalline powder.

後処理

  1. filtrationThe catalyst was filtered off
  2. concentrationthe filtrate was concentrated to dryness under reduced pressure

出典と根拠

ORDレコード
ord-1e898b3b8cd242da9b7bcf2cb7f72955
出典データセット
uspto-grants-2004_04
特許番号
US06716863B2

反応ノート

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