Boron tribromide → 3-(7-Hydroxybenzo(b)furan-2-yl)-5-methyl-1,2,4-oxadiazole

HRID 2085142ノート

反応式

C[O:2][C:3]1[C:8]2[O:9][C:10]([C:12]3[N:16]=[C:15]([CH3:17])[O:14][N:13]=3)=[CH:11][C:7]=2[CH:6]=[CH:5][CH:4]=1.B(Br)(Br)Br>>[OH:2][C:3]1[C:8]2[O:9][C:10]([C:12]3[N:16]=[C:15]([CH3:17])[O:14][N:13]=3)=[CH:11][C:7]=2[CH:6]=[CH:5][CH:4]=1

参加物

反応物 2

HCID 25134Boron tribromide

HCID 227293143-(7-Methoxybenzo(b)furan-2-yl)-5-methyl-1,2,4-oxadiazole

生成物 1

HCID 227290843-(7-Hydroxybenzo(b)furan-2-yl)-5-methyl-1,2,4-oxadiazole収率 94%

実験手順

By the reactions in the same manner as in Starting Material Synthesis Example 5 using 3-(7-methoxybenzo(b)furan-2-yl)-5-methyl-1,2,4-oxadiazole (1.7 g) and boron tribromide (6.5 ml), the title compound (1.5 g) was obtained as white crystals.

出典と根拠

ORDレコード: ord-7f055f965aff4288849cec01acd79657
出典データセット: uspto-grants-2004_04
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US06720320B2

反応ノート

読み込み中…