化工社化工社 化学情報印刷レポート · 研究参考用
trans-2-Phenyl-1-cyclopropanecarbonyl chloride → 2-(ethoxymethyl)-6,7-dimethyl-1-[2-(1-{[(1R*,2R*)-2-phenylcyclopropyl]carbonyl}piperidin-4-yl)ethyl]-1H-imidazo[4,5-c]pyridin-4-amine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | trans-2-Phenyl-1-cyclopropanecarbonyl chloride | HCID 13656 | — |
| 反応物 | 2-(ethoxymethyl)-6,7-dimethyl-1-(2-piperidin-4-ylethyl)-1H-imidazo[4,5-c]pyridin-4-amine | HCID 12972962 | — |
| 生成物 | 2-(ethoxymethyl)-6,7-dimethyl-1-[2-(1-{[(1R*,2R*)-2-phenylcyclopropyl]carbonyl}piperidin-4-yl)ethyl]-1H-imidazo[4,5-c]pyridin-4-amine | HCID 20575807 | — |
反応手順
Using the method of Examples 61-75, trans-2-phenyl-1-cyclopropanecarbonyl chloride was reacted with 2-(ethoxymethyl)-6,7-dimethyl-1-(2-piperidin-4-ylethyl)-1H-imidazo[4,5-c]pyridin-4-amine to provide the desired product. The observed accurate mass was 476.3039.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06720333B2 |
| 出典データセット | uspto-grants-2004_04 |
| ORD ID | ord-e2bb503e3ad44b20a17cb451e19b78a1 |
| 出典メモ | uspto-grants-2004_04 |