Methanol → 1-(difluoromethyl)-3-{4-[(1-methyl-1H-benzimidazol-2-yl)oxy]phenyl}-1,3-dihydro-2H-imidazo[4,5-b]pyridin-2-one

反応式

[CH3:39][OH:40].[Cl:1][c:2]1[n:3][c:4]2[c:5]([n:6]1[CH3:7])[cH:8][cH:9][cH:10][cH:11]2.[F:12][CH:13]([n:14]1[c:15](=[O:30])[n:16](-[c:23]2[cH:24][cH:25][c:26]([OH:29])[cH:27][cH:28]2)[c:17]2[n:18][cH:19][cH:20][cH:21][c:22]12)[F:31].[H-:33].[Na+:32].[O:34]=[CH:35][N:36]([CH3:37])[CH3:38]>>[c:2]1([O:29][c:26]2[cH:25][cH:24][c:23](-[n:16]3[c:15](=[O:30])[n:14]([CH:13]([F:12])[F:31])[c:22]4[c:17]3[n:18][cH:19][cH:20][cH:21]4)[cH:28][cH:27]2)[n:3][c:4]2[c:5]([n:6]1[CH3:7])[cH:8][cH:9][cH:10][cH:11]2