Sodium Hydroxide → HCID 22724875、化合物

HRID 2086562

反応式

HRID 2086562 の反応式
C[O:2][C:3]([C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=1[NH:11][C:12](=[O:24])/[CH:13]=[CH:14]/[C:15]1[CH:20]=[CH:19][CH:18]=[C:17]([N+:21]([O-:23])=[O:22])[CH:16]=1)=[O:4].[OH-].[Na+]>CO>[C:3]([C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=1[NH:11][C:12](=[O:24])/[CH:13]=[CH:14]/[C:15]1[CH:20]=[CH:19][CH:18]=[C:17]([N+:21]([O-:23])=[O:22])[CH:16]=1)([OH:4])=[O:2]

参加物

4

反応物 2

HCID 14798Sodium HydroxideHCID 692365methyl 2-[(2E)-3-(3-nitrophenyl)prop-2-enoylamino]benzoate

生成物 1

HCID 22724875HCID 22724875、化合物

試薬・触媒・溶媒 1

HCID 887Methanol溶媒

実験手順

500 mg (1.53 mmol) of trans-3-nitrocinnamic acid-N-(2-methoxycarbonyl-phenyl)-amide are stirred into a mixture of 20 ml of methanol and 8 ml of 2N sodium hydroxide solution for two hours at 50° C. Then the methanol is distilled off in vacuo, the residue is diluted with about 150 ml of water and adjusted to about pH 2.5 with stirring. The product which is then precipitated is suction filtered, washed with about 10 ml of water and dried.

後処理

  1. distillationThen the methanol is distilled off in vacuo
  2. additionthe residue is diluted with about 150 ml of water
  3. customThe product which is then precipitated
  4. filtrationfiltered
  5. washwashed with about 10 ml of water
  6. customdried

出典と根拠

ORDレコード
ord-6ed9cdad5340498287da76fd7f799bf4
出典データセット
uspto-grants-2004_04
特許番号
US06727250B2

関連ノート

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