Sodium Bicarbonate → 2-Methyl-4-(3-aminophenyl)-3-oxo-3,4-dihydropyrido[2,3-b]pyrazine
反応式
[CH3:1][C:2]1[C:7](=[O:8])[N:6]([C:9]2[CH:14]=[CH:13][CH:12]=[C:11]([NH:15]C(=O)C)[CH:10]=2)[C:5]2[N:19]=[CH:20][CH:21]=[CH:22][C:4]=2[N:3]=1.C(=O)(O)[O-].[Na+]>Cl>[CH3:1][C:2]1[C:7](=[O:8])[N:6]([C:9]2[CH:14]=[CH:13][CH:12]=[C:11]([NH2:15])[CH:10]=2)[C:5]2[N:19]=[CH:20][CH:21]=[CH:22][C:4]=2[N:3]=1参加物
4
実験手順
The suspension of 2-methyl-4-(3-acetamidophenyl)-3-oxo-3,4-dihydropyrido[2,3-b]pyrazine (8.6 g) in 3N hydrochloric acid (50 ml) was refluxed for an hour. The mixture was made basic by sodium bicarbonate (15 g) to obtain 2-methyl-4-(3-aminophenyl)-3-oxo-3,4-dihydropyrido[2,3-b]pyrazine (7.4 g) in yellow powder.
後処理
- temperaturewas refluxed for an hour
出典と根拠
- ORDレコード
- ord-1ec11489a9c4418ca17b989498132347
- 出典データセット
- uspto-grants-2004_04
- 特許番号
- US06727245B2
反応ノート
読み込み中…