Methyl Bromide → HCID 86587173、化合物

HRID 2087098ノート

反応式

HRID 2087098 の反応式
[CH3:1][N:2]([C:4]([CH2:7][C:8]([CH3:11])([CH3:10])[CH3:9])([CH3:6])[CH3:5])[CH3:3].[CH3:12][Br:13]>ClCCl>[Br-:13].[CH3:3][N+:2]([C:4]([CH2:7][C:8]([CH3:11])([CH3:10])[CH3:9])([CH3:5])[CH3:6])([CH3:12])[CH3:1]

参加物

4

反応物 2

HCID 6323Methyl BromideHCID 221336n,n,2,4,4-pentamethylpentan-2-amine

生成物 1

HCID 86587173HCID 86587173、化合物

試薬・触媒・溶媒 1

HCID 6344Dichloromethane溶媒

実験手順

The procedure given in the previous example was followed. Starting with a solution of N,N-dimethyl t-octylamine (5 g, 31.8 mmol) in dichloromethane (5 mL) and methyl bromide (2.0 M solution in t-butyl methyl ether, 42.8 mL, 85.6 mmol), product was obtained as a white solid (7.2 g (90%)). 1H NMR (CDCl3): δ3.35 (s, 9H, —N+(CH3)3), 1.79 (s, 2H, —CH2—), 1.60 (bt, 6H, —C(CH3)2—), 1.11 (s, 9H, —C(CH3)3) ppm.

後処理

  1. customproduct was obtained as a white solid (7.2 g (90%))

出典と根拠

ORDレコード
ord-a2072f1fdde44317a5964b660b5931a6
出典データセット
uspto-grants-2004_04
特許番号
US06727387B2

反応ノート

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