2-methyl-N-[3-(4-piperidyl)phenyl]propanamide → N-(3-{1-[(2S)-3-(4-Chlorophenoxy)-2-methylpropyl]-4-piperidinyl}phenyl)-2-methylpropanamide
反応式
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([O:8][CH2:9][C@@H:10]([CH3:13])[CH2:11]Cl)=[CH:4][CH:3]=1.[CH3:14][CH:15]([CH3:31])[C:16]([NH:18][C:19]1[CH:24]=[CH:23][CH:22]=[C:21]([CH:25]2[CH2:30][CH2:29][NH:28][CH2:27][CH2:26]2)[CH:20]=1)=[O:17]>>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([O:8][CH2:9][C@@H:10]([CH3:13])[CH2:11][N:28]2[CH2:29][CH2:30][CH:25]([C:21]3[CH:20]=[C:19]([NH:18][C:16](=[O:17])[CH:15]([CH3:14])[CH3:31])[CH:24]=[CH:23][CH:22]=3)[CH2:26][CH2:27]2)=[CH:4][CH:3]=1参加物
3
実験手順
Prepared by Procedure G and Scheme B1 using 1-chloro-4-{[(2R)-3-chloro-2-methylpropyl]oxy}benzene and 2-methyl-N-[3-(4-piperidinyl)phenyl]propanamide: ESMS m/e: 429.2 (M+H)+.
後処理
- customPrepared by Procedure G and Scheme B1
出典と根拠
- ORDレコード
- ord-a02e198af108416d9ac5c2643b0a58eb