4-Hydroxy-4-(6-methoxypyridin-3-yl)cyclohexan-1-one → HCID 54755921、化合物

HRID 2089133

反応式

HRID 2089133 の反応式
OC(C(F)(F)F)=O.[NH:8]1[CH2:11][CH:10]([NH:12][C:13](=[O:29])[CH2:14][NH:15][C:16]2[C:20]3[CH:21]=[C:22]([C:25]([F:28])([F:27])[F:26])[CH:23]=[CH:24][C:19]=3[O:18][N:17]=2)[CH2:9]1.[OH:30][C:31]1([C:38]2[CH:39]=[N:40][C:41]([O:44][CH3:45])=[CH:42][CH:43]=2)[CH2:36][CH2:35][C:34](=O)[CH2:33][CH2:32]1>>[OH:30][C:31]1([C:38]2[CH:39]=[N:40][C:41]([O:44][CH3:45])=[CH:42][CH:43]=2)[CH2:32][CH2:33][CH:34]([N:8]2[CH2:11][CH:10]([NH:12][C:13](=[O:29])[CH2:14][NH:15][C:16]3[C:20]4[CH:21]=[C:22]([C:25]([F:27])([F:26])[F:28])[CH:23]=[CH:24][C:19]=4[O:18][N:17]=3)[CH2:9]2)[CH2:35][CH2:36]1

参加物

3

反応物 2

HCID 529879954-Hydroxy-4-(6-methoxypyridin-3-yl)cyclohexan-1-oneHCID 86660176N-Azetidin-3-yl-2-(5-trifluoromethyl-benzo[d]isoxazol-3-ylamino)-acetamide TFA salt

生成物 1

HCID 54755921HCID 54755921、化合物

実験手順

The title compound was prepared as a white solid from reaction of (N-Azetidin-3-yl-2-(5-trifluoromethyl-benzo[d]isoxazol-3-ylamino)-acetamide TFA salt (as prepared in Example 1, Step D) and 4-hydroxy-4-(6-methoxy-pyridin-3-yl)-cyclohexanone, using the procedure described in Step E of Example 1.

出典と根拠

ORDレコード
ord-3ba82ce0e26c4f1f9e19f1603a4c99b4
出典データセット
uspto-grants-2013_05
特許番号
US08436023B2

関連ノート

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