化工社化工社 化学情報印刷レポート · 研究参考用
4-Oxocyclohexane-1-carbonitrile → N-[1-(4-Cyano-cyclohexyl)-azetidin-3-yl]-2-(5-trifluoromethyl-benzo[d]isoxazol-3-ylamino)-acetamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 4-Oxocyclohexane-1-carbonitrile | HCID 12235639 | — |
| 反応物 | N-Azetidin-3-yl-2-(5-trifluoromethyl-benzo[d]isoxazol-3-ylamino)-acetamide TFA salt | HCID 86660176 | — |
| 生成物 | N-[1-(4-Cyano-cyclohexyl)-azetidin-3-yl]-2-(5-trifluoromethyl-benzo[d]isoxazol-3-ylamino)-acetamide | HCID 54756152 | — |
反応手順
The title compound was prepared as a white solid from reaction of (N-Azetidin-3-yl-2-(5-trifluoromethyl-benzo[d]isoxazol-3-ylamino)-acetamide TFA salt (as prepared in Example 1, Step D) and 4-cyano-cyclohexanone using the procedure described in Step E of Example 1.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08436023B2 |
| 出典データセット | uspto-grants-2013_05 |
| ORD ID | ord-074db556be4c472781f63884bf813fa4 |
| 出典メモ | uspto-grants-2013_05 |