Ammonia → 6-Methylnicotinamide
反応式
[CH3:1][C:2]1[CH:11]=[CH:10][C:5]([C:6](OC)=[O:7])=[CH:4][N:3]=1.[NH3:12]>>[CH3:1][C:2]1[CH:11]=[CH:10][C:5]([C:6]([NH2:12])=[O:7])=[CH:4][N:3]=1参加物
3
実験手順
A mixture of methyl 6-methylnicotinate (13.9 g) and 28% aqueous ammonia (140 mL) was stirred at room temperature for 4 hr. The reaction mixture was concentrated under reduced pressure, and the residue was recrystallized from ethanol to give the title compound as a white solid (yield 8.98 g, 72%).
後処理
- concentrationThe reaction mixture was concentrated under reduced pressure
- customthe residue was recrystallized from ethanol
出典と根拠
- ORDレコード
- ord-2f4e026cb32e40909c09107827329388
- 出典データセット
- uspto-grants-2013_05
- 特許番号
- US08436187B2
反応ノート
読み込み中…