化工社化工社 化学情報印刷レポート · 研究参考用
Benzoic acid, 3,5-dibromo- → 1-(3,5-Dibromophenyl)ethanone
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Benzoic acid, 3,5-dibromo- | HCID 12063 | — |
| 反応物 | HCID 178418348 | HCID 178418348 | — |
| 溶媒 | Diethyl Ether | HCID 3283 | — |
| 生成物 | 1-(3,5-Dibromophenyl)ethanone | HCID 621825 | — |
反応手順
To a solution of 3,5-dibromobenzoic acid (2.5 g, 8.9 mmol) in Et2O (30 mL) at 0° C. was added methyl lithium (1.6M in diethyl ether; 12.3 mL, 19.6 mmol) was added dropwise. The reaction was warmed to room temperature and stirred for 2 hours. Acidic work-up, followed by silica gel chromatography, gave 1-(3,5-dibromo-phenyl)-ethanone.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08440707B2 |
| 出典データセット | uspto-grants-2013_05 |
| ORD ID | ord-fffc4f752e7c47718bb1a72eaefedc93 |
| 出典メモ | uspto-grants-2013_05 |