1-(3,5-Dibromophenyl)ethanone → (r)-1-(3,5-Dibromo-phenyl)-ethanol

HRID 2092490

反応式

HRID 2092490 の反応式
[Br:1][C:2]1[CH:3]=[C:4]([C:9](=[O:11])[CH3:10])[CH:5]=[C:6]([Br:8])[CH:7]=1.B1(C)OC(C2C=CC=CC=2)(C2C=CC=CC=2)[C@H]2N1CCC2>>[Br:1][C:2]1[CH:3]=[C:4]([C@H:9]([OH:11])[CH3:10])[CH:5]=[C:6]([Br:8])[CH:7]=1

参加物

3

反応物 2

HCID 6218251-(3,5-Dibromophenyl)ethanoneHCID 2734713(3aS)-1-methyl-3,3-diphenyl-hexahydropyrrolo(1,2-c)(1,3,2)oxazaborole

生成物 1

HCID 58539463(r)-1-(3,5-Dibromo-phenyl)-ethanol

実験手順

1-(3,5-dibromo-phenyl)-ethanone and (S)-(−)-2-methyl-CBS-oxazaborolidine were reacted as described in Example 35, Step 1 to provide (R)-1-(3,5-dibromo-phenyl)-ethanol.

出典と根拠

ORDレコード
ord-a3746b822b54429db57ae5da9339f211
出典データセット
uspto-grants-2013_05
特許番号
US08440707B2

関連ノート

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