HCID 72428139、化合物 → Methyl 2-methyl-3-sulfanylbutanoate

HRID 2093247ノート

反応式

HRID 2093247 の反応式
C([S:4][CH:5]([CH3:12])[CH:6]([CH3:11])[C:7]([O:9][CH3:10])=[O:8])(=O)C>CO>[SH:4][CH:5]([CH3:12])[CH:6]([CH3:11])[C:7]([O:9][CH3:10])=[O:8]

参加物

3

反応物 1

HCID 72428139HCID 72428139、化合物

生成物 1

HCID 79398463Methyl 2-methyl-3-sulfanylbutanoate収率 44%

試薬・触媒・溶媒 1

HCID 887Methanol溶媒

実験手順

Conditions are the same as for Example 2, but with the product of Example 3 as the starting component and methanol as solvent; 44% yield. Odor: at 0.1 ppm in DPG—onions, green vegetable, peach, tropical fruit, metallic. GC/MS (EI): m/z (%) 148(46), 115(25), 88(100), 61(64), 59(100). 1H NMR (CDCl3): δ 3.69 (s mix of isomers, 3H), 3.13-3.30 (m, 1H), 2.48-2.58 (m, 1H), 1.66 & 1.51 (2d, J=7.34 Hz, 1H mix of diastereomers), 1.31-1.34 (2d mix of isomers, J=6.87 Hz, 3H), 1.18-1.27 (2d mix of isomers, J=6.87 Hz, 3H). 13C NMR (CDCl3) for mix of diastereomers: δ 175.0, 51.9, 51.6, 48.7, 47.6, 37.7, 37.1, 23.5, 21.9, 14.3, 13.5.

後処理

  1. addition13C NMR (CDCl3) for mix of diastereomers

出典と根拠

ORDレコード
ord-a9e73c1a123e4e2295a38247c56187e9
出典データセット
uspto-grants-2013_05
特許番号
US08445051B2

反応ノート

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