4-Bromobenzyl bromide → 1-Bromo-4-((methylsulfonyl)methyl)benzene

HRID 2093453

反応式

HRID 2093453 の反応式
[Br:1][C:2]1[CH:9]=[CH:8][C:5]([CH2:6]Br)=[CH:4][CH:3]=1.[CH3:10][S:11]([O:13][Na])=[O:12]>C(O)C>[CH3:10][S:11]([CH2:6][C:5]1[CH:8]=[CH:9][C:2]([Br:1])=[CH:3][CH:4]=1)(=[O:13])=[O:12]

参加物

4

反応物 2

HCID 685274-Bromobenzyl bromideHCID 178504973HCID 178504973、化合物

生成物 1

HCID 27614151-Bromo-4-((methylsulfonyl)methyl)benzene

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

p-Bromobenzyl bromide (500 mg, 2 mmol) was refluxed with MeSO2Na (306 mg, 3 mmol) in Ethanol for 1 hour. The reaction was cooled, concentrated and purified by flash column (50% acetone/hexanes) to give the desired product.

後処理

  1. temperatureThe reaction was cooled
  2. concentrationconcentrated
  3. custompurified by flash column (50% acetone/hexanes)

出典と根拠

ORDレコード
ord-4e14562e96cb4dd0b49ba042177958d4
出典データセット
uspto-grants-2013_05
特許番号
US08445499B2

関連ノート

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