化工社化工社 化学情報印刷レポート · 研究参考用
Lithium Hydroxide → 3-(2-Chloroethoxy)propanoic acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Lithium Hydroxide | HCID 3939 | — |
| 反応物 | Ethyl 3-(2-chloro-ethoxy)-propionate | HCID 85848654 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | 3-(2-Chloroethoxy)propanoic acid | HCID 343680 | — |
反応手順
2.00 g (11.1 mmol) ethyl 3-(2-chloro-ethoxy)-propionate are suspended in 8 ml of ethanol and 4.96 ml (16.6 mmol) of 8% lithium hydroxide solution are added. The mixture is stirred for 4 hours at ambient temperature, then evaporated down i. vac., acidified with 2-molar hydrochloric acid, combined with diethyl ether and dried over sodium sulphate. Then it is filtered off and evaporated down i. vac.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08445525B2 |
| 出典データセット | uspto-grants-2013_05 |
| ORD ID | ord-70abbf213c354f598da129b70fc1419a |
| 出典メモ | uspto-grants-2013_05 |