Butanal → N-(1,1-Dimethylethyl)-1-butanamine

反応式

[C:1]([NH2:5])([CH3:4])([CH3:3])[CH3:2].[CH3:6][CH2:7][CH:8]=O.[CH:10](=O)[CH2:11][CH2:12][CH3:13]>>[C:1]([NH:5][CH2:6][CH2:7][CH3:8])([CH3:4])([CH3:3])[CH3:2].[CH2:10]([NH:5][C:1]([CH3:4])([CH3:3])[CH3:2])[CH2:11][CH2:12][CH3:13]

参加物

反応物 3

HCID 261Butanal

HCID 527Propanal

HCID 6385Tert-Butylamine

生成物 2

HCID 85447N-(1,1-Dimethylethyl)-1-butanamine

HCID 12426736N-(1,1-Dimethylethyl)-1-propanamine

実験手順

In an analogous manner to that in example 1c, 1.5 mol of tert-butylamine were reacted with n-propionaldehyde (example 2a) or n-butyraldehyde (example 2b) to give the corresponding secondary amines (tert-butylpropylamine and n-butyl-tert-butylamine respectively), and they were then analyzed by gas chromatography. For these reactions too, yields of 93.6 area % (example 2a) and 95.7 area % (example 2b) of the corresponding secondary amines were achieved.