3-Ethoxy-4-(pyridin-4-ylamino)cyclobut-3-ene-1,2-dione → 3-[6-(4-Trifluoromethylphenoxy)-hexylamino]-4-(pyridin-4-yl-amino)-cyclobut-3-ene-1,2-dione
反応式
C(O[C:4]1[C:5](=[O:16])[C:6](=[O:15])[C:7]=1[NH:8][C:9]1[CH:14]=[CH:13][N:12]=[CH:11][CH:10]=1)C.[F:17][C:18]([F:34])([F:33])[C:19]1[CH:32]=[CH:31][C:22]([O:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][NH2:30])=[CH:21][CH:20]=1>>[F:17][C:18]([F:33])([F:34])[C:19]1[CH:32]=[CH:31][C:22]([O:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][NH:30][C:4]2[C:5](=[O:16])[C:6](=[O:15])[C:7]=2[NH:8][C:9]2[CH:10]=[CH:11][N:12]=[CH:13][CH:14]=2)=[CH:21][CH:20]=1参加物
3
実験手順
The title compound was prepared according to the procedure described in example 1B starting from 3-ethoxy-4-(pyridin-4-yl-amino)-3-cyclobutene-1,2-dione prepared according to example 7A and 6-(4-trifluoromethylphenoxy)-hexylamine. The reaction mixture was heated to reflux for 4 hours instead of stirring 18 h at r.t.
後処理
- customprepared
- temperatureThe reaction mixture was heated
- temperatureto reflux for 4 hours instead