Methyl bromoacetate → [8-Chloro-4-methyl-2-oxo-3-(4-pyrazol-1-ylbenzyl)-1,2-dihydroquinolin-5-yloxy]acetic acid methyl ester

反応式

[CH3:27][O:28][C:29]([CH2:30][Br:31])=[O:32].[Cl:1][c:2]1[cH:3][cH:4][c:5]([OH:26])[c:6]2[c:7]([CH3:25])[c:8]([CH2:13][c:14]3[cH:15][cH:16][c:17](-[n:20]4[n:21][cH:22][cH:23][cH:24]4)[cH:18][cH:19]3)[c:9](=[O:12])[nH:10][c:11]12>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([O:26][CH2:30][C:29]([O:28][CH3:27])=[O:32])[c:6]2[c:7]([CH3:25])[c:8]([CH2:13][c:14]3[cH:15][cH:16][c:17](-[n:20]4[n:21][cH:22][cH:23][cH:24]4)[cH:18][cH:19]3)[c:9](=[O:12])[nH:10][c:11]12

参加物

反応物 2

HCID 60984Methyl bromoacetate

HCID 674579118-chloro-5-hydroxy-4-methyl-3-(4-pyrazol-1-ylbenzyl)-1H-quinolin-2-one

生成物 1

HCID 67459078[8-Chloro-4-methyl-2-oxo-3-(4-pyrazol-1-ylbenzyl)-1,2-dihydroquinolin-5-yloxy]acetic acid methyl ester

出典と根拠

ORDレコード: ord-68cf29aaa0cf43898034c94b40dc1a9c
出典データセット: Training data from https://doi.org/10.1039/C8SC04228D (6/10)
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…