Cesium carbonate → methyl ((1R)-6-(((2-(butyloxy)-2'-fluoro-5'-(methyloxy)-1,1'-biphenyl-4-yl)methyl)oxy)-2,3-dihydro-1H-inden-1-yl)acetate

反応式

[OH:1][C:2]1[CH:10]=[C:9]2[C:5]([CH2:6][CH2:7][C@H:8]2[CH2:11][C:12]([O:14][CH3:15])=[O:13])=[CH:4][CH:3]=1.C(=O)([O-])[O-].[Cs+].[Cs+].[CH2:22]([O:26][C:27]1[CH:32]=[C:31]([CH2:33]Cl)[CH:30]=[CH:29][C:28]=1[C:35]1[CH:40]=[C:39]([O:41][CH3:42])[CH:38]=[CH:37][C:36]=1[F:43])[CH2:23][CH2:24][CH3:25]>CN(C=O)C.O>[CH2:22]([O:26][C:27]1[CH:32]=[C:31]([CH2:33][O:1][C:2]2[CH:10]=[C:9]3[C:5]([CH2:6][CH2:7][C@@H:8]3[CH2:11][C:12]([O:14][CH3:15])=[O:13])=[CH:4][CH:3]=2)[CH:30]=[CH:29][C:28]=1[C:35]1[CH:40]=[C:39]([O:41][CH3:42])[CH:38]=[CH:37][C:36]=1[F:43])[CH2:23][CH2:24][CH3:25].[CH2:22]([O:26][C:27]1[CH:32]=[C:31]([CH2:33][O:1][C:2]2[CH:10]=[C:9]3[C:5]([CH2:6][CH2:7][C@H:8]3[CH2:11][C:12]([O:14][CH3:15])=[O:13])=[CH:4][CH:3]=2)[CH:30]=[CH:29][C:28]=1[C:35]1[CH:40]=[C:39]([O:41][CH3:42])[CH:38]=[CH:37][C:36]=1[F:43])[CH2:23][CH2:24][CH3:25]