1H-Pyrazol-3-amine, 5-methyl- → HCID 178486651、化合物
反応式
[Br:1][C:2]1[C:3]([O:14][CH3:15])=[CH:4][C:5]([CH2:11][C:12]#[N:13])=[C:6]([CH:10]=1)[C:7]([OH:9])=O.[NH2:16][C:17]1[CH:21]=[C:20]([CH3:22])[NH:19][N:18]=1>C(O)(=O)C>[Br:1][C:2]1[CH:10]=[C:6]2[C:5]([CH:11]=[C:12]([NH:16][C:17]3[CH:21]=[C:20]([CH3:22])[NH:19][N:18]=3)[N:13]=[C:7]2[OH:9])=[CH:4][C:3]=1[O:14][CH3:15]参加物
4
実験手順
Similar procedure as described in example 9B was used, starting from 5-Bromo-2-cyanomethyl-4-methoxy-benzoic acid, 3-amino-5-methylpyrazol and acetic acid to give 7-Bromo-6-methoxy-3-(5-methyl-1H-pyrazol-3-ylamino)-isoquinolin-1-ol. LC-MS: m/e 349 (MH+).
出典と根拠
- ORDレコード
- ord-b664972ad2d842b09d707147cee698a0
- 出典データセット
- uspto-grants-2009_08
- 特許番号
- US07572809B2
反応ノート
読み込み中…