p-Fluorophenethylamine → [2-(4-Fluoro-phenyl)-ethyl]-(4-trimethylsilanyl-benzyl)-amine
反応式
[CH3:1][Si:2]([CH3:12])([CH3:11])[C:3]1[CH:10]=[CH:9][C:6]([CH:7]=O)=[CH:5][CH:4]=1.[F:13][C:14]1[CH:19]=[CH:18][C:17]([CH2:20][CH2:21][NH2:22])=[CH:16][CH:15]=1>>[F:13][C:14]1[CH:19]=[CH:18][C:17]([CH2:20][CH2:21][NH:22][CH2:7][C:6]2[CH:9]=[CH:10][C:3]([Si:2]([CH3:12])([CH3:11])[CH3:1])=[CH:4][CH:5]=2)=[CH:16][CH:15]=1参加物
3
実験手順
[2-(4-fluoro-phenyl)-ethyl]-(4-trimethylsilanyl-benzyl)-amine was prepared in analogy to example 1 from 4-trimethylsilanyl-benzaldehyde and 2-(4-fluoro-phenyl)-ethylamine. MS (ISP): 302.2 (100) (M+H)+. 1H NMR (CDCl3, 300 MHz): δ 7.47 (d, 2H), 7.27 (d, 2H), 7.15 (dd, 2H), 6.97 (dt, 2H) 3.79 (s, 2H), 2.75-3.00 (m, 4H), 0.26 (s, 9H).
出典と根拠
- ORDレコード
- ord-97c9275eebd0421684e5020ca4098fd6
- 出典データセット
- uspto-grants-2009_08
- 特許番号
- US07572823B2
反応ノート
読み込み中…