Hexylamine → N-Hexyl-4,5-diphenyl-1-methylimidazole-2-carboxamide

反応式

[CH2:1]([NH2:7])[CH2:2][CH2:3][CH2:4][CH2:5][CH3:6].[C:8]1([C:14]2[N:15]=[C:16]([C:26](O)=[O:27])[N:17]([CH3:25])[C:18]=2[C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1>>[CH2:1]([NH:7][C:26]([C:16]1[N:17]([CH3:25])[C:18]([C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)=[C:14]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)[N:15]=1)=[O:27])[CH2:2][CH2:3][CH2:4][CH2:5][CH3:6]

参加物

反応物 2

HCID 8102Hexylamine

HCID 22066062HCID 22066062、化合物

生成物 1

HCID 9968913N-Hexyl-4,5-diphenyl-1-methylimidazole-2-carboxamide

実験手順

Using essentially the same procedure as Example 4, Step B, but using n-hexylamine (0.025 mL), 4,5-diphenyl-1-methylimidazole-2-carboxylic acid (30 mg, 0.10 mmol) from Example 4, Step A was converted to the title compound.

出典と根拠

ORDレコード: ord-311c54fc21404739ab5b772e1d336733
出典データセット: uspto-grants-2009_08
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US07572785B2

反応ノート

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