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HRID 2104478作成日：2026年10月27日

1,1'-Biphenyl-4-yl-boronic acid → [4-(1,1'-Biphenyl-4-yl)-8-(Trifluoromethyl)Quinolin-3-yl](Pyridin-2-yl)Methanone

https://huagongshe.com/reaction/2104478

反応式

関与物質

役割名称HCID仕込み量
反応物1,1'-Biphenyl-4-yl-boronic acidHCID 151253—
反応物(4-Chloro-8-trifluoromethyl-quinolin-3-yl)-pyridin-2-yl-methanoneHCID 66913162—
生成物[4-(1,1'-Biphenyl-4-yl)-8-(Trifluoromethyl)Quinolin-3-yl](Pyridin-2-yl)MethanoneHCID 11396865—

反応手順

This compound was prepared using the procedure of Example 1, step 5 using (4-chloro-8-trifluoromethyl-quinolin-3-yl)-pyridin-2-yl-methanone in place of [4-chloro-8-(trifluoromethyl)quinolin-3-yl](phenyl)methanone and 4-(phenyl)phenylboronic acid in place of phenyl boronic acid. MS (ESI) m/z 455 ([M+H]+); Anal. Calcd for C28H17F3N2O: C, 74.00; H, 3.77; N, 6.16. Found: C, 73.99; H, 3.81; N, 5.92.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US07576215B2
出典データセットuspto-grants-2009_08
ORD IDord-06866ebc32124b64894cf40fa1cf27c8
出典メモuspto-grants-2009_08