[4-Chloro-8-(trifluoromethyl)quinolin-3-yl](phenyl)methanone → N-{3-[3-Benzoyl-8-(Trifluoromethyl)Quinolin-4-yl]Benzyl}-N'-(2-Fluorophenyl)Urea
反応式
[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[NH:8][C:9](=[O:21])[NH:10][CH2:11][C:12]1[CH:17]=[CH:16][C:15](B(O)O)=[CH:14][CH:13]=1.Cl[C:23]1[C:32]2[C:27](=[C:28]([C:33]([F:36])([F:35])[F:34])[CH:29]=[CH:30][CH:31]=2)[N:26]=[CH:25][C:24]=1[C:37]([C:39]1[CH:44]=[CH:43][CH:42]=[CH:41][CH:40]=1)=[O:38]>>[C:37]([C:24]1[CH:25]=[N:26][C:27]2[C:32]([C:23]=1[C:14]1[CH:13]=[C:12]([CH:17]=[CH:16][CH:15]=1)[CH2:11][NH:10][C:9]([NH:8][C:3]1[CH:4]=[CH:5][CH:6]=[CH:7][C:2]=1[F:1])=[O:21])=[CH:31][CH:30]=[CH:29][C:28]=2[C:33]([F:36])([F:34])[F:35])(=[O:38])[C:39]1[CH:40]=[CH:41][CH:42]=[CH:43][CH:44]=1参加物
3
実験手順
The title compound was prepared from 4-[3-(2-Fluoro-phenyl)-ureidomethyl]phenylboronic acid and [4-chloro-8-(trifluoromethyl)quinolin-3-yl](phenyl)methanone according to the procedure of Example 1. MS (ES) m/z 541.9.
出典と根拠
- ORDレコード
- ord-41deac266ed44398895079f093e04e0e
- 出典データセット
- uspto-grants-2009_08