戻る
化工社化工社 化学情報印刷レポート · 研究参考用
HRID 2105730作成日：2026年10月27日

Dabco → 1-[4'-(4-{1-(4-Fluorophenyl)-3-[3-(4-fluorophenyl)-3-hydroxypropyl]4-oxoazetidin-2-yl}phenoxymethyl)biphenyl-4-ylmethyl]-4-aza-1-azoniabicyclo[2.2.2]octane bromide

https://huagongshe.com/reaction/2105730

反応式

関与物質

役割名称HCID仕込み量
反応物DabcoHCID 9237—
反応物4-[4-(4'-Bromomethylbiphenyl-4-ylmethoxy)phenyl]-1-(4-fluorophenyl)-3-[3-(4-fluorophenyl)-3-hydroxypropyl]azetidin-2-oneHCID 21083191—
溶媒TolueneHCID 1140—
生成物1-[4'-(4-{1-(4-Fluorophenyl)-3-[3-(4-fluorophenyl)-3-hydroxypropyl]4-oxoazetidin-2-yl}phenoxymethyl)biphenyl-4-ylmethyl]-4-aza-1-azoniabicyclo[2.2.2]octane bromideHCID 21083159—

反応手順

Compound (21) and DABCO were dissolved in toluene and reacted analogously to Example IV, giving the product (22) as a colorless solid of molecular weight 780.76 (C44H44BrF2N3O3); MS (ESI): 700.3 (MH+).

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US07579339B2
出典データセットuspto-grants-2009_08
ORD IDord-5d8038c9335a4806aa2fbbb8550fbf1c
出典メモuspto-grants-2009_08