Potassium Hydroxide → 3-(1-carboxyethoxy)-5-methyl-1-phenyl-1,2,4-1H-triazole
反応式
C([O:3][C:4]([CH:6]([O:8][C:9]1[N:13]=[C:12]([CH3:14])[N:11]([C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)[N:10]=1)[CH3:7])=[O:5])C.[OH-].[K+]>C(O)C>[C:4]([CH:6]([O:8][C:9]1[N:13]=[C:12]([CH3:14])[N:11]([C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)[N:10]=1)[CH3:7])([OH:5])=[O:3]参加物
4
実験手順
Ten g of the compound of Example 7 was refluxed for 4 hours with 4.1 g of potassium hydroxide in 150 ml of ethanol and the product was collected by extraction with ethyl acetate. The extract was washed with water, dried and evaporated under vacuum, and the residue was recrystallized from toluene to obtain 2.1 g of the desired product, m.p. 157°-159°.
後処理
- customthe product was collected by extraction with ethyl acetate
- washThe extract was washed with water
- customdried
- customevaporated under vacuum
- customthe residue was recrystallized from toluene
出典と根拠
- ORDレコード
- ord-d4f75632c6ef44ec9f5ef44d75695263
- 出典データセット
- uspto-grants-1990_06
- 特許番号
- US04931083
反応ノート
読み込み中…