Hydrochloric Acid → 5-(2-Aminothiazol-4-ylmethylene)rhodanine-3-acetic acid
反応式
C([NH:20][C:21]1[S:22][CH:23]=[C:24]([CH:26]=[C:27]2[S:31][C:30](=[S:32])[N:29]([CH2:33][C:34]([O-:36])=[O:35])[C:28]2=[O:37])[N:25]=1)(C1C=CC=CC=1)(C1C=CC=CC=1)C1C=CC=CC=1.[NH2+]1CCCCC1.Cl>O1CCOCC1>[NH2:20][C:21]1[S:22][CH:23]=[C:24]([CH:26]=[C:27]2[S:31][C:30](=[S:32])[N:29]([CH2:33][C:34]([OH:36])=[O:35])[C:28]2=[O:37])[N:25]=1参加物
4
実験手順
A mixture comprising 2.2 g of piperidinium 5-(2-tritylaminothiazol-4-ylmethylene)rhodanine-3-acetate and 30 ml of a 4N dioxane solution of hydrogen chloride was stirred at room temperature for 30 minutes, and the resulting mixture was left to stand overnight. The crystalline product which precipitated out was collected by filtration and washed with dioxane, giving the desired compound as a brownish-orange powder.