Ethyl bromopyruvate → Ethyl 2-isopropylaminothiazole-4-carboxylate

HRID 2107302ノート

反応式

HRID 2107302 の反応式
[CH:1]([NH:4][C:5]([NH2:7])=[S:6])([CH3:3])[CH3:2].Br[CH2:9][C:10](=O)[C:11]([O:13][CH2:14][CH3:15])=[O:12]>C(O)C>[CH:1]([NH:4][C:5]1[S:6][CH:9]=[C:10]([C:11]([O:13][CH2:14][CH3:15])=[O:12])[N:7]=1)([CH3:3])[CH3:2]

参加物

4

反応物 2

HCID 66144Ethyl bromopyruvateHCID 1711921Urea, 1-isopropyl-2-thio-

生成物 1

HCID 15053549Ethyl 2-isopropylaminothiazole-4-carboxylate

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

The reaction described in Preparation 42 was repeated, but using 3.7 g of isopropylthiourea, 7.4 g of ethyl bromopyruvate and 50 ml of ethanol, giving the title compound as a pale yellow oil.

後処理

  1. customThe reaction described in Preparation 42

出典と根拠

ORDレコード
ord-975a0b793e334788b6c424fd96bd50b6
出典データセット
uspto-grants-1990_06
特許番号
US04933355

反応ノート

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