3-cyclopropyl-2-methyl-3H-imidazole-4-carbaldehyde → 5,6,7,8-Tetrahydroimidazo[1,2-a]pyridine-3-carbaldehyde

HRID 2109226

反応式

HRID 2109226 の反応式
Cl.N1CCCCC1=N.BrC(=COC(C)C)C=O.[CH:18]1([N:21]2[C:25]([CH:26]=[O:27])=[CH:24][N:23]=[C:22]2[CH3:28])[CH2:20][CH2:19]1>>[N:23]1[CH:24]=[C:25]([CH:26]=[O:27])[N:21]2[CH2:18][CH2:20][CH2:19][CH2:28][C:22]=12

参加物

4

反応物 3

HCID 210973073-cyclopropyl-2-methyl-3H-imidazole-4-carbaldehydeHCID 534166342-Bromo-3-isopropoxy-propenalHCID 178479080HCID 178479080、化合物

生成物 1

HCID 111162275,6,7,8-Tetrahydroimidazo[1,2-a]pyridine-3-carbaldehyde

実験手順

5,6,7,8-Tetrahydro-imidazo[1,2-a]pyridine-3-carbaldehyde (2:1 with 5,6,7,8-Tetrahydro-imidazo[1,2-a]pyridine-2-carbaldehyde) was prepared from piperidin-2-ylideneamine hydrochloride (Aldrich) and 2-bromo-3-isopropoxy-propenal in the same manner as cyclopropyl-2-methyl-3H-imidazole-4-carbaldehyde (Example 45).

出典と根拠

ORDレコード
ord-6d195c005b064b548432225f07d95c53
出典データセット
uspto-grants-2009_04
特許番号
US07514458B2

関連ノート

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