3-Azido-4-methylbenzoic acid → 3-Azido-N-(5-tert-butyl-3-methanesulfonylamino-2-methyl-phenyl)-4-methyl-benzamide

HRID 2109289ノート

反応式

HRID 2109289 の反応式
[N:1]([C:4]1[CH:5]=[C:6]([CH:10]=[CH:11][C:12]=1[CH3:13])[C:7]([OH:9])=O)=[N+:2]=[N-:3].[NH2:14][C:15]1[C:16]([CH3:30])=[C:17]([NH:25][S:26]([CH3:29])(=[O:28])=[O:27])[CH:18]=[C:19]([C:21]([CH3:24])([CH3:23])[CH3:22])[CH:20]=1.N(C1C=C(C=CC=1C)C(NC1C=C(C(C)(C)C)C=C(NS(C)(=O)=O)C=1OC)=O)=[N+]=[N-]>>[N:1]([C:4]1[CH:5]=[C:6]([CH:10]=[CH:11][C:12]=1[CH3:13])[C:7]([NH:14][C:15]1[CH:20]=[C:19]([C:21]([CH3:23])([CH3:24])[CH3:22])[CH:18]=[C:17]([NH:25][S:26]([CH3:29])(=[O:28])=[O:27])[C:16]=1[CH3:30])=[O:9])=[N+:2]=[N-:3]

参加物

4

反応物 3

HCID 179730913-Azido-4-methylbenzoic acidHCID 210792023-azido-N-(5-tert-butyl-3-methanesulfonylamino-2-methoxy-phenyl)-4-methyl-benzamideHCID 21097367N-(3-Amino-5-tert-butyl-2-methyl-phenyl)-methanesulfonamide

生成物 1

HCID 210973043-Azido-N-(5-tert-butyl-3-methanesulfonylamino-2-methyl-phenyl)-4-methyl-benzamide

実験手順

3-Azido-N-(5-tert-butyl-3-methanesulfonylamino-2-methyl-phenyl)-4-methyl-benzamide was prepared from 3-azido-4-methyl benzoic acid (US 04/102492) and N-(3-Amino-5-tert-butyl-2-methyl-phenyl)-methanesulfonamide in the same manner as 3-azido-N-(5-tert-butyl-3-methanesulfonylamino-2-methoxy-phenyl)-4-methyl-benzamide (Example 15).

出典と根拠

ORDレコード
ord-77bcacd4a29e4babbe3d8c4965e933ad
出典データセット
uspto-grants-2009_04
特許番号
US07514458B2

反応ノート

読み込み中…