HCID 14096412、化合物 → HCID 13174771、化合物

反応式

[C:1]1([CH:7]([O:14][C:15]([CH:17]2[N:21]3[C:22](=[O:25])[CH:23](Br)[C@H:20]3[S:19](=[O:26])[C:18]2([CH3:28])[CH3:27])=[O:16])[C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.C1(C(OC(C2N3C(=O)C(Br)(Br)[C@H]3S(=O)C2(C)C)=O)C2C=CC=CC=2)C=CC=CC=1>>[C:1]1([CH:7]([O:14][C:15]([CH:17]2[N:21]3[C:22](=[O:25])[CH2:23][C@H:20]3[S:19](=[O:26])[C:18]2([CH3:28])[CH3:27])=[O:16])[C:8]2[CH:9]=[CH:10][CH:11]=[CH:12][CH:13]=2)[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

参加物

反応物 2

HCID 14096412HCID 14096412、化合物2 回

HCID 68995161HCID 68995161、化合物2 回

生成物 1

HCID 13174771HCID 13174771、化合物収率 90%

実験手順

The same reaction as in Example 2 were conducted except that 6-bromo-2,2-dimethylpenam-3-carboxylic acid 1-oxide diphenylmethyl ester (Compound 3) [compound of the formula (1) wherein X═Br, Y═H, R=diphenylmethyl, n=1] was used in place of Compound 1 to obtain Compound 2 in a yield of 90%.

後処理

customThe same reaction as in Example 2

出典と根拠

ORDレコード: ord-88771e297c9149baa3e3bd88f240bc71
出典データセット: uspto-grants-2009_04
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US07514553B2

反応ノート

読み込み中…