3-Bromo-4-methoxybenzoic acid → Ethyl 3-bromo-4-methoxybenzoate

HRID 2109390ノート

反応式

HRID 2109390 の反応式
Br[C:2]1C=CO[C:3]=1C(O)=O.[Br:10][C:11]1[CH:12]=[C:13]([CH:17]=[CH:18][C:19]=1[O:20][CH3:21])[C:14]([OH:16])=[O:15]>>[Br:10][C:11]1[CH:12]=[C:13]([CH:17]=[CH:18][C:19]=1[O:20][CH3:21])[C:14]([O:16][CH2:2][CH3:3])=[O:15]

参加物

3

反応物 2

HCID 668363-Bromo-4-methoxybenzoic acidHCID 6054793-Bromofuran-2-carboxylic acid

生成物 1

HCID 23062539Ethyl 3-bromo-4-methoxybenzoate

実験手順

A reaction was carried out in the same manner as in Reference Example 1 except that the 3-bromo-2-furancarboxylic acid used in Reference Example 1 was replaced with 3-bromo-4-methoxybenzoic acid (4.62 g). The crude product was purified by silica gel column chromatography (eluent: ethyl acetate/hexane=1/10), thereby giving 4.65 g of ethyl 3-bromo-4-methoxybenzoate.

後処理

  1. customThe crude product was purified by silica gel column chromatography (eluent: ethyl acetate/hexane=1/10)

出典と根拠

ORDレコード
ord-4b46e69b70fd4b4aa893cbd58bfefb1d
出典データセット
uspto-grants-2009_04
特許番号
US07514452B2

反応ノート

読み込み中…