AR-R-17779 → HCID 11738867、化合物

HRID 2109466ノート

反応式

HRID 2109466 の反応式
[O:1]1[C@@:5]2([CH:10]3[CH2:11][CH2:12][N:7]([CH2:8][CH2:9]3)[CH2:6]2)[CH2:4][NH:3][C:2]1=[O:13].Br[C:15]1[CH:19]=[C:18]([C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][N:21]=2)[O:17][CH:16]=1>[Cu]I>[N:21]1[CH:22]=[CH:23][CH:24]=[CH:25][C:20]=1[C:18]1[O:17][CH:16]=[C:15]([N:3]2[CH2:4][C@:5]3([CH:10]4[CH2:11][CH2:12][N:7]([CH2:8][CH2:9]4)[CH2:6]3)[O:1][C:2]2=[O:13])[CH:19]=1

参加物

4

反応物 2

HCID 5310971AR-R-17779HCID 576342462-(4-Bromofuran-2-yl)pyridine

生成物 1

HCID 11738867HCID 11738867、化合物

試薬・触媒・溶媒 1

HCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)触媒

実験手順

The title compound was prepared by a method analogous to that described in Preparation 3 from (S)-spiro[1-azabicyclo[2.2.2]octan-3,5′-oxazolidin]-2′-one and 3-bromo-5-(2-pyridyl)-furan with 2 equivalents of copper (I) iodide. The title compound (90 mg) was obtained as a pale yellow solid, m/z 342 (MH+).

後処理

  1. customThe title compound was prepared by a method analogous to

出典と根拠

ORDレコード
ord-5879e6bad96441b0a020d584de063a02
出典データセット
uspto-grants-2009_04
特許番号
US07514567B2

反応ノート

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