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5-Amino-2-hydroxybenzimidazole → 2-(4-Benzyl-piperidin-1-yl)-2-oxo-N-(2-oxo-2,3-dihydro-1H-benzimidazol-5-yl)-acetamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 5-Amino-2-hydroxybenzimidazole | HCID 66765 | — |
| 反応物 | (4-Benzylpiperidin-1-yl)oxoacetic acid | HCID 16110264 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | 2-(4-Benzyl-piperidin-1-yl)-2-oxo-N-(2-oxo-2,3-dihydro-1H-benzimidazol-5-yl)-acetamide | HCID 10177679 | — |
反応手順
The title compound is prepared from (4-benzyl-piperidin-1-yl)-oxo-acetic acid (Example 5b) and 5-amino-1,3-dihydro-benzimidazol-2-one according to the method described in Example 2. Melting Point: >260° C. (water)
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07435744B2 |
| 出典データセット | uspto-grants-2008_10 |
| ORD ID | ord-643f0b867e734a74bccf5cef1ff75002 |
| 出典メモ | uspto-grants-2008_10 |