4-(4-Methylphenoxy)piperidine → 2-Oxo-N-(3-oxo-3,4-dihydro-2H-benzo[1,4]oxazin-7-yl)-2-(4-p-tolyloxy-piperidin-1-yl)-acetamide

HRID 2115015

反応式

HRID 2115015 の反応式
[O:1]=[C:2]1[NH:7][C:6]2[CH:8]=[CH:9][C:10]([NH:12][C:13](=[O:17])[C:14]([OH:16])=O)=[CH:11][C:5]=2[O:4][CH2:3]1.[C:18]1([CH3:31])[CH:23]=[CH:22][C:21]([O:24][CH:25]2[CH2:30][CH2:29][NH:28][CH2:27][CH2:26]2)=[CH:20][CH:19]=1>C(OCC)C>[O:16]=[C:14]([N:28]1[CH2:29][CH2:30][CH:25]([O:24][C:21]2[CH:22]=[CH:23][C:18]([CH3:31])=[CH:19][CH:20]=2)[CH2:26][CH2:27]1)[C:13]([NH:12][C:10]1[CH:9]=[CH:8][C:6]2[NH:7][C:2](=[O:1])[CH2:3][O:4][C:5]=2[CH:11]=1)=[O:17]

参加物

4

反応物 2

HCID 38374974-(4-Methylphenoxy)piperidineHCID 69100554N-(3-oxo-3,4-dihydro-2H-benzo[1,4]oxazin-7-yl)-oxalamic acid

生成物 1

HCID 691005912-Oxo-N-(3-oxo-3,4-dihydro-2H-benzo[1,4]oxazin-7-yl)-2-(4-p-tolyloxy-piperidin-1-yl)-acetamide

試薬・触媒・溶媒 1

HCID 3283Diethyl Ether溶媒

実験手順

The title compound is prepared from N-(3-oxo-3,4-dihydro-2H-benzo[1,4]oxazin-7-yl)-oxalamic acid (Example 53b) and 4-p-tolyloxy-piperidine according to the method described in Example 1c. Melting Point: 226-228° C. (diethylether)

出典と根拠

ORDレコード
ord-78927e00b1884962bef7cdefdc71e396
出典データセット
uspto-grants-2008_10
特許番号
US07435744B2

関連ノート

読み込み中…