p-Toluidine → 2-(4-Benzyl-piperidin-1-yl)-N-(4-methyl-phenyl)-2-oxo-acetamide

HRID 2115042

反応式

HRID 2115042 の反応式
[CH2:1]([CH:8]1[CH2:13][CH2:12][N:11]([C:14](=[O:18])[C:15]([OH:17])=O)[CH2:10][CH2:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH3:19][C:20]1[CH:26]=[CH:25][C:23]([NH2:24])=[CH:22][CH:21]=1>C(OCC)C>[CH2:1]([CH:8]1[CH2:9][CH2:10][N:11]([C:14](=[O:18])[C:15]([NH:24][C:23]2[CH:25]=[CH:26][C:20]([CH3:19])=[CH:21][CH:22]=2)=[O:17])[CH2:12][CH2:13]1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

参加物

4

反応物 2

HCID 7813p-ToluidineHCID 16110264(4-Benzylpiperidin-1-yl)oxoacetic acid

生成物 1

HCID 449019072-(4-Benzyl-piperidin-1-yl)-N-(4-methyl-phenyl)-2-oxo-acetamide

試薬・触媒・溶媒 1

HCID 3283Diethyl Ether溶媒

実験手順

The title compound is prepared from (4-benzyl-piperidin-1-yl)-oxo-acetic acid (Example 5b) and 4-methyl-aniline (Aldrich) according to the method described in Example 1c. Melting Point: 115-117° C. (diethylether)

出典と根拠

ORDレコード
ord-b75ebf04f5774de8a77fdfc9d5b78ede
出典データセット
uspto-grants-2008_10
特許番号
US07435744B2

関連ノート

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