Potassium Iodide → 1-Methyl-5-nitroquinolin-1-ium iodide

HRID 2117319ノート

反応式

HRID 2117319 の反応式
[N+:1]([C:4]1[CH:13]=[CH:12][CH:11]=[C:10]2[C:5]=1[CH:6]=[CH:7][CH:8]=[N:9]2)([O-:3])=[O:2].S(OC)(O[CH3:18])(=O)=O.[I-:21].[K+]>O>[I-:21].[CH3:18][N+:9]1[C:10]2[C:5](=[C:4]([N+:1]([O-:3])=[O:2])[CH:13]=[CH:12][CH:11]=2)[CH:6]=[CH:7][CH:8]=1

参加物

5

反応物 3

HCID 4875Potassium IodideHCID 6497Dimethyl SulfateHCID 118295-Nitroquinoline

生成物 1

HCID 124950501-Methyl-5-nitroquinolin-1-ium iodide

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

5-Nitroquinoline (4 g, 30 mmol) was melted at 85° C., prior to addition of dimethyl sulfate (2.2 ml, 30 mmol), and the resulting mixture was stirred at this temperature for 1.5 hours. The yellow gel was dissolved in water (35 ml) and cooled to room temperature. A saturated aqueous solution of potassium iodide (7.63 g, 45.9 mmol) was added, and the resulting orange precipitate was filtered, washing the residue with chilled water. After drying under vacuum at 60° C., for 2 hours, the brick-red solid was used in the next step without purification.

後処理

  1. filtrationthe resulting orange precipitate was filtered
  2. washwashing the residue with chilled water
  3. customAfter drying under vacuum at 60° C., for 2 hours
  4. customthe brick-red solid was used in the next step without purification

出典と根拠

ORDレコード
ord-ec8fbf85c3ab4e498eea5f7341e343fd
出典データセット
uspto-grants-2008_10
特許番号
US07442701B2

反応ノート

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