化工社化工社 化学情報印刷レポート · 研究参考用
7-Amino-4-vinylisoindolinone → 7-Amino-4-ethylisoindolinone
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 7-Amino-4-vinylisoindolinone | HCID 68488659 | — |
| 反応物 | HCID 178418361 | HCID 178418361 | — |
| 触媒 | Palladium | HCID 23938 | — |
| 溶媒 | Dimethylformamide | HCID 6228 | — |
| 生成物 | 7-Amino-4-ethylisoindolinone | HCID 68490969 | 102.8% |
反応手順
7-Amino-4-vinylisoindolinone (50.0 mg, 0.287 mmol) was dissolved in DMF (2.5 mL), and the solution was added with 10% Pd—C (10 mg) followed by stirring at room temperature for 1.8 hours under normal pressure and hydrogen atmosphere. The reaction mixture was filtered using Celite and the solvent of the filtrate was evaporated under reduced pressure to obtain 7-amino-4-ethylisoindolinone (52.0 mg, quantitative).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07745641B2 |
| 出典データセット | uspto-grants-2010_06 |
| ORD ID | ord-9b574fe409a9418d963834a7bf341de1 |
| 出典メモ | uspto-grants-2010_06 |