化工社化工社 化学情報印刷レポート · 研究参考用
Potassium Carbonate → 2-(2-Chloroethoxy)benzene-1-sulfonamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Potassium Carbonate | HCID 11430 | — |
| 反応物 | 2-Hydroxybenzene-1-sulfonamide | HCID 637546 | — |
| 反応物 | 2-Chloroethyl p-toloylsulfonate | HCID 53969867 | — |
| 溶媒 | Methyl Ethyl Ketone | HCID 6569 | — |
| 生成物 | 2-(2-Chloroethoxy)benzene-1-sulfonamide | HCID 13729454 | — |
反応手順
A mixture of 9.0 g of 2-hydroxyphenylsulfonamide, 7.9 g of potassium carbonate, 13.3 g of 2-chloroethyl p-toloylsulfonate and 80 ml of ethylmethylketone is refluxed for 40 hours. The reaction mixture is cooled to room temperature, filtrated and evaporated to dryness. From the oily residue crystallise after addition of a small portion of methylene chloride 7.0 g of 2-(2-chloroethoxy)-phenylsulfonamide, m.p. 110° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04681619 |
| 出典データセット | uspto-grants-1987_07 |
| ORD ID | ord-086e0da574614fe2b03935b0070c2db1 |
| 出典メモ | uspto-grants-1987_07 |