4-[(4-fluorophenyl)amino]-1-methyl-1H-pyrazole-5-carboxylic acid → 5-FLUORO-1-METHYL-1,4-DIHYDRO-9H-PYRAZOLO[4,3-b]QUINOLIN-9-ONE

HRID 2119617

反応式

HRID 2119617 の反応式
[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[NH:8][C:9]1[CH:10]=[N:11][N:12]([CH3:17])[C:13]=1[C:14]([OH:16])=O.FC1C=CC(NC2C=NN(C)C=2C(O)=O)=CC=1>>[F:1][C:2]1[C:3]2[NH:8][C:9]3[CH:10]=[N:11][N:12]([CH3:17])[C:13]=3[C:14](=[O:16])[C:4]=2[CH:5]=[CH:6][CH:7]=1

参加物

3

反応物 2

HCID 129856934-[(4-fluorophenyl)amino]-1-methyl-1H-pyrazole-5-carboxylic acidHCID 129856954-[(2-fluorophenyl)amino]-1-methyl-1H-pyrazole-5-carboxylic acid

生成物 1

HCID 129856965-FLUORO-1-METHYL-1,4-DIHYDRO-9H-PYRAZOLO[4,3-b]QUINOLIN-9-ONE

実験手順

The title compound was prepared according to the procedure of step 2 in EXAMPLE 1 (CJ-022998) using 4-[(2-fluorophenyl)amino]-1-methyl-1H-pyrazole-5-carboxylic acid (EXAMPLE 2, step 1), instead of 4-[(4-fluorophenyl)amino]-1-methyl-1H-pyrazole-5-carboxylic acid.

出典と根拠

ORDレコード
ord-11a8c2c1b7f743138466d08d7696c4ea
出典データセット
uspto-grants-2004_02
特許番号
US06686373B2

関連ノート

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