Lithium borohydride → (E)-7-[3-(3,4-bis-Hydroxymethylbenzyloxy)phenyl]-3-ethyloct-6-en-3-ol
反応式
[CH2:1]([C:3]([OH:33])([CH2:31][CH3:32])[CH2:4][CH2:5]/[CH:6]=[C:7](/[C:9]1[CH:10]=[C:11]([CH:28]=[CH:29][CH:30]=1)[O:12][CH2:13][C:14]1[CH:15]=[C:16]([C:24](OC)=[O:25])[C:17](=[CH:22][CH:23]=1)[C:18](OC)=[O:19])\[CH3:8])[CH3:2].[BH4-].[Li+]>>[OH:25][CH2:24][C:16]1[CH:15]=[C:14]([CH:23]=[CH:22][C:17]=1[CH2:18][OH:19])[CH2:13][O:12][C:11]1[CH:10]=[C:9](/[C:7](/[CH3:8])=[CH:6]/[CH2:5][CH2:4][C:3]([CH2:31][CH3:32])([OH:33])[CH2:1][CH3:2])[CH:30]=[CH:29][CH:28]=1参加物
3
実験手順
In a manner similar to Example 53(e), by reacting 131 mg (0.29 mmol) of dimethyl 4-[3-((E)-5-ethyl-5-hydroxy-1-methylhept-1-enyl)phenoxymethyl]phthalate with 25 mg (1.15 mmol) of lithium borohydride, a colourless oil is obtained (m=89 mg; Y=78%).
後処理
- customa colourless oil is obtained (m=89 mg; Y=78%)
出典と根拠
- ORDレコード