Diazomethane → 2,4,5-Trimethylisoxazol-3(2H)-one
反応式
[OH:1][C:2]1[C:6]([CH3:7])=[C:5]([CH3:8])[O:4][N:3]=1.[N+](=[CH2:11])=[N-]>CCOCC>[CH3:11][N:3]1[C:2](=[O:1])[C:6]([CH3:7])=[C:5]([CH3:8])[O:4]1参加物
4
実験手順
To a solution of 3-hydroxy-4,5-dimethylisoxazole (7 g, 62 mmol) in ether (50 mL) was added diazomethane until a persistent yellow colour was obtained. The reaction was stirred for another 30 min at room temperature. The ether was evaporated off and the residue purified by column chromatography on silica gel using ether as eluent. 4 g of the desired material was obtained.
後処理
- customwas obtained
- customThe ether was evaporated off
- customthe residue purified by column chromatography on silica gel
出典と根拠
- ORDレコード
- ord-106c5a73609441c0bb0ac152402a1ea8
- 出典データセット
- uspto-grants-2004_02
- 特許番号
- US06693111B1
反応ノート
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