Hydrochloric Acid → HCID 69702667、化合物
反応式
[OH:1][CH:2]([CH3:20])[CH2:3][CH2:4][C:5]1[CH:10]=[C:9]([O:11][CH3:12])[CH:8]=[CH:7][C:6]=1[NH:13]C(=O)C(C)(C)C.C(O)C.[ClH:24]>O>[Cl-:24].[OH:1][C@H:2]([CH3:20])[CH2:3][CH2:4][C:5]1[CH:10]=[C:9]([O:11][CH3:12])[CH:8]=[CH:7][C:6]=1[NH3+:13]参加物
5
実験手順
A mixture of the the product from Step B (7.31 g, 2.29 mmol), ethanol (100 mL), concentrated HCl (50 mL) and water (30 mL) was heated at reflux for three days. The volatile material was removed by evaporation and the residue was dried overnight. The residue was triturated with ethyl acetate, filtered and dried under a vacuum to give an amorphous powder (4.11 g, 68%).
後処理
- temperaturewas heated
- temperatureat reflux for three days
- customThe volatile material was removed by evaporation
- customthe residue was dried overnight
- customThe residue was triturated with ethyl acetate
- filtrationfiltered
- customdried under a vacuum
出典と根拠
- ORDレコード
- ord-9b1f17d7df5240c1ad4150b61e22c110
- 出典データセット
- uspto-grants-2004_02
- 特許番号
- US06696476B2
反応ノート
読み込み中…