2-(5-Acetyl-2-ethylaminophenylimino)-3-pyridin-3-ylmethyl-thiazolidin-4-one → 2-(5-acetyl-2-ethylaminophenylimino)-5-(3-methyl-4,5,6,7-tetrahydro-3H-benzothiazol-2-ylidene)-3-pyridin-3-ylmethylthiazolidin-4-one

HRID 2121994ノート

反応式

HRID 2121994 の反応式
C1(C)C=CC(S([O-])(=O)=O)=CC=1.[CH3:12][N+:13]1[C:17]2[CH2:18][CH2:19][CH2:20][CH2:21][C:16]=2[S:15][C:14]=1SC.[C:24]([C:27]1[CH:28]=[CH:29][C:30]([NH:47][CH2:48][CH3:49])=[C:31]([N:33]=[C:34]2[N:38]([CH2:39][C:40]3[CH:41]=[N:42][CH:43]=[CH:44][CH:45]=3)[C:37](=[O:46])[CH2:36][S:35]2)[CH:32]=1)(=[O:26])[CH3:25]>>[C:24]([C:27]1[CH:28]=[CH:29][C:30]([NH:47][CH2:48][CH3:49])=[C:31]([N:33]=[C:34]2[N:38]([CH2:39][C:40]3[CH:41]=[N:42][CH:43]=[CH:44][CH:45]=3)[C:37](=[O:46])[C:36](=[C:14]3[N:13]([CH3:12])[C:17]4[CH2:18][CH2:19][CH2:20][CH2:21][C:16]=4[S:15]3)[S:35]2)[CH:32]=1)(=[O:26])[CH3:25]

参加物

3

反応物 2

HCID 219374722-(5-Acetyl-2-ethylaminophenylimino)-3-pyridin-3-ylmethyl-thiazolidin-4-oneHCID 219375263-Methyl-2-methylthio-4,5,6,7-tetrahydrobenzothiazol-3-ium p-toluenesulfonate

生成物 1

HCID 726398812-(5-acetyl-2-ethylaminophenylimino)-5-(3-methyl-4,5,6,7-tetrahydro-3H-benzothiazol-2-ylidene)-3-pyridin-3-ylmethylthiazolidin-4-one

実験手順

The title compound was prepared in a manner similar to Example 168 by condensing intermediate 3-methyl-2-methylthio-4,5,6,7-tetrahydrobenzothiazol-3-ium p-toluenesulfonate with 2-(5-acetyl-2-ethylaminophenylimino)-3-pyridin-3-ylmethyl-thiazolidin-4-one. MS(ESI): 520 (MH+).

出典と根拠

ORDレコード
ord-f1fb034e1350430a8128e4c29fd786ca
出典データセット
uspto-grants-2004_02
特許番号
US06696473B2

反応ノート

読み込み中…