m-Nitroacetophenone → 2-Chloro-1-(3-nitrophenyl)ethanone
反応式
[N+:1]([C:4]1[CH:5]=[C:6]([C:10](=[O:12])[CH3:11])[CH:7]=[CH:8][CH:9]=1)([O-:3])=[O:2].S(Cl)([Cl:16])(=O)=O>C(OC)(C)(C)C>[Cl:16][CH2:11][C:10]([C:6]1[CH:7]=[CH:8][CH:9]=[C:4]([N+:1]([O-:3])=[O:2])[CH:5]=1)=[O:12]参加物
4
実験手順
3′-Nitroacetophenone (2.00 g) was suspended in methyl t-butyl ether (12.1 ml), and sulfuryl chloride (4.90 g) was dropwise added thereto at 20° C. over 15 minutes. After stirring for 2 hours, precipitated solids were filtered and washed with methyl t-butyl ether. Drying under reduced pressure yielded the desired 2-chloro-3′-nitroacetophenone (1.62 g; 67.0%).
後処理
- customprecipitated solids
- filtrationwere filtered
- washwashed with methyl t-butyl ether
- customDrying under reduced pressure
出典と根拠
- ORDレコード
- ord-bcabfbf82f8e4999a0c5bba15cd4169a
- 出典データセット
- uspto-grants-2004_02
- 特許番号
- US06696573B1
反応ノート
読み込み中…