Cyclopropylamine → HCID 86589545、化合物

反応式

Cl[C:2]1[C:7]([C:8](OCC)=[S:9])=[CH:6][N:5]=[C:4]([CH3:13])[N:3]=1.[CH:14]1([NH2:17])[CH2:16][CH2:15]1>>[CH:14]1([NH:17][C:2]2[C:7]([CH:8]=[S:9])=[CH:6][N:5]=[C:4]([CH3:13])[N:3]=2)[CH2:16][CH2:15]1

参加物

反応物 2

HCID 69828Cyclopropylamine

HCID 53249641Ethyl 4-chloro-2-methylthio-pyrimidine-5-carboxylate

生成物 1

HCID 86589545HCID 86589545、化合物

実験手順

The 4-cyclopropylamino-2-methylthiopyrimidine-5-carboxaldehyde was prepared as described in Example 1 (steps A through C) starting with ethyl 4-chloro-2-methylthiopyrimidine-5-carboxylate (Aldrich Chemical Co.) and cyclopropyl amine (Aldrich Chemical Co.).

出典と根拠

ORDレコード: ord-c8c2fca238ad40c7b887f18fe46d224f
出典データセット: uspto-grants-2004_02
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US06696566B2

反応ノート

読み込み中…