Dimethyl Sulfoxide → 5-isopropyl-N-[6-chloro-5-(o-methoxyphenoxy)-2-methyl-4-pyrimidinyl]-2-pyridine sulfonamide

HRID 2126972ノート

反応式

HRID 2126972 の反応式
[CH3:33][S:34]([CH3:35])=[O:36].[CH:20]([CH3:21])([CH3:22])[c:23]1[cH:24][cH:25][c:26]([S:29](=[O:30])(=[O:31])[NH2:32])[n:27][cH:28]1.[Cl:1][c:2]1[n:3][c:4]([CH3:18])[n:5][c:6]([Cl:17])[c:7]1[O:8][c:9]1[c:10]([O:15][CH3:16])[cH:11][cH:12][cH:13][cH:14]1.[K:19].[OH2:37]>>[c:2]1([NH:32][S:29]([c:26]2[cH:25][cH:24][c:23]([CH:20]([CH3:21])[CH3:22])[cH:28][n:27]2)(=[O:30])=[O:31])[n:3][c:4]([CH3:18])[n:5][c:6]([Cl:17])[c:7]1[O:8][c:9]1[c:10]([O:15][CH3:16])[cH:11][cH:12][cH:13][cH:14]1

参加物

6

反応物 5

HCID 679Dimethyl SulfoxideHCID 962WaterHCID 5462222PotassiumHCID 181841935-Isopropylpyridine-2-sulfonamideHCID 219795994,6-Dichloro-5-(o-methoxyphenoxy)-2-methyl-pyrimidine

生成物 1

HCID 227294015-isopropyl-N-[6-chloro-5-(o-methoxyphenoxy)-2-methyl-4-pyrimidinyl]-2-pyridine sulfonamide

出典と根拠

ORDレコード
ord-d95c4475a79d47a99e50f93dacf61e1d
出典データセット
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

反応ノート

読み込み中…